Antinociceptive effects of tDCS are dependent on the polarity of the stimulation

Takeaway

  • Transcranial direct current stimulation (tDCS) affects neuronal networks differentially depending on the polarity of the stimulation, whereby anodal stimulation causes an increase in activation.

Why this matters

  • Understanding the mechanisms of the neuromodulatory effects of tDCS on the brain may help to further the use of this safe, non-invasive and painless therapy.