The role of endovascular thrombectomy versus medical management in patients with large vessel occlusion

  • A retrospective, observational cohort study evaluating 301 patients with occlusions in the internal carotid artery or middle cerebral artery, receiving either endovascular thrombectomy (EVT; n=185) or medical management (n=116).
  • EVT was associated with higher odds of functional independence (38% vs control, 10%; [inverse probability treatment weighting adjusted odds ratio (IPTW aOR)], 4.56; 95% CI 2.28–9.09; P<0.001), and lower odds of mortality (26% vs control, 41%; IPTW aOR, 0.49; 95% CI 0.27–0.89; P=0.02).
  • EVT was however associated with increased odds of symptomatic intracranial hemorrhage (10.1% vs control, 1.7%; IPTW aOR, 10.65; 95% CI 2.19–51.69; P=0.003).